- Giant Knotweed Rhizome
- Polygoni Cuspidati Rhizoma et Radix
|Medicinal Group||Dampness-draining anti-icteric medicinal|
Dried rhizome and root of Polygonum cuspidatum Sieb. et Zucc. (Fam. Polygonaceae)
|Nature and Flavors||slightly bitter; slightly cold|
|Meridian Affinity||Liver, Lung, Gallbladder|
To dispel wind and damp, eliminate blood stasis and alleviate pain, relieve cough, and resolve phlegm
Arthralgia; jaundice caused by damp-heat; amenorrhea; mass formation in the abdomen; cough with profuse expectoration; scalds and burns; traumatic injuries; carbuncles and sores
- Application of Dannang Recipe No. 2 (consisted of giant knotweed rhizome) in perioperative stage of laparoscopic cholecystectomy can effectively promote the recovery of postoperative gastrointestinal motility and suppress the occurrence of acute inflammation.
- Tangyikang decoction (consisted of giant knotweed rhizome) could improve the function of islet beta-cell in patients with latent autoimmune diabetes mellitus in adults. 
- Detoxifying and blood circulation activating Chinese herb extraction of polygonum cuspidatum and hawthorn has good effect of anti-atherosclerosis and promoting plaque stability.
Use with caution in pregnancy
Pro-oxidative effects on G6PD-deficient erythrocytes in vitro 
Dry mouth, nausea, vomiting, diarrhea 
- Xu L, Jiang J, Du FZ. (2008). Application of dannang recipe no. 2 in the perioperative stage of laparoscopic cholecystectomy. Zhongguo Zhong Xi Yi Jie He Za Zhi. , 28(12):1090-2.
- Xu XW, Zhang DX. (2008). Effect of Tangyikang in improving the function of pancreatic islet beta cells in patients with latent autoimmune diabetes mellitus in adults. Zhongguo Zhong Xi Yi Jie He Za Zhi. , 28(10):882-5.
- Liu LT, Zheng GJ, Zhang WG, Guo G, Wu M. (2014). Clinical study on treatment of carotid atherosclerosis with extraction of polygoni cuspidati rhizoma et radix and crataegi fructus: a randomized controlled trial. Zhongguo Zhong Yao Za Zhi. , 39(6):1115-9.
- Ko CH, Li K, Ng PC, Fung KP, Wong R, Chui KM, Gu G, Yung E, Fok TF (2008) Pro- oxidative effects of Chinese herbal medicine on G6PD- deficient erythrocytes in vitro. TOXICOLOGY IN VITRO, 22, 5, 1222-1227.
- 童麗平 (2002)。<口服虎杖煎劑致消化道不良反應1例>。時珍國醫國藥，5。