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American Ginseng
Panacis Quinquefolii Radix
Medicinal Group Qi-tonifying medicinal

Dried root of Panax quinquefolium L. (Fam. Aralianceae)

Nature and Flavors slightly bitter, sweet; cool
Meridian Affinity Heart, Lung, Kidney

To tonify qi and nourish yin, remove heat and engender fluids



Part used

Root and Rhizome


Used for deficiency of qi and yin, internal-heat, cough and asthma, bloody phlegm, fire in the deficiency syndrome, dysphoria and tiredness, diabetes, dry and thirsty mouth and throat

Research Findings

  • A cup of American ginseng infusion could protect cellular DNA from oxidative stress at least within 2 h. [1]
  • American ginseng has been shown to be effective in improving glycemic control in type 2 diabetes through increasing post-prandial insulin levels and decreasing postprandial glycemic response.[2]
  • P. quinquefolius (a ginsenoside-rich extract of American ginseng) can acutely benefit working memory and extend the age range of this effect to middle-aged individuals.[3]
  • Robust working memory enhancement may be identified following administration of American ginseng.[4]
  • North American ginseng exerts a neutral acute effect on blood pressure in hypertensive individuals.[5]
  • Addition of American ginseng extract to conventional therapy in diabetes with concomitant hypertension improved arterial stiffness and attenuated systolic blood pressure. [6]


Incompatible with Rhizoma et Radix Veratri

Report on adverse effect

Allergic reactions, arrhythmia aggravated, female endocrine disorders, reduce the effect of nerve block, spleen asthenia syndrome [7]

Insomnia, headache, chest discomfort, and diarrhea; diabetes mellitus [8]



  1. Szeto YT, Sin YS, Pak SC, Kalle W. (2015). American ginseng tea protects cellular DNA within 2 h from consumption: results of a pilot study in healthy human volunteers. Int J Food Sci Nutr. , 66(7):815-8. doi: 10.3109/09637486.2015.1088937. Epub 2015 Sep 22.
  2. Mucalo I, Rahelić D, Jovanovski E, Bozikov V, Romić Z, Vuksan V. (2012). Effect of American ginseng (Panax quinquefolius L.) on glycemic control in type 2 diabetes. Coll Antropol. , 36(4):1435-40.
  3. Ossoukhova A, Owen L, Savage K, Meyer M, Ibarra A, Roller M, Pipingas A, Wesnes K, Scholey A. (2015). Improved working memory performance following administration of a single dose of American ginseng (Panax quinquefolius L.) to healthy middle-age adults. Hum Psychopharmacol. , 30(2):108-22. doi: 10.1002/hup.2463.
  4. Scholey A, Ossoukhova A, Owen L, Ibarra A, Pipingas A, He K, Roller M, Stough C. (2010). Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study. Psychopharmacology (Berl). , 212(3):345-56. doi: 10.1007/s00213-010-1964-y. Epub 2010 Jul 31.
  5. Stavro PM, Woo M, Heim TF, Leiter LA, Vuksan V. (2005). North American ginseng exerts a neutral effect on blood pressure in individuals with hypertension. Hypertension. , 46(2):406-11. Epub 2005 Jul 5.
  6. Mucalo I, Jovanovski E, Rahelić D, Božikov V, Romić Z, Vuksan V. (2013). Effect of American ginseng (Panax quinquefolius L.) on arterial stiffness in subjects with type-2 diabetes and concomitant hypertension. J Ethnopharmacol. , 150(1):148-53. doi: 10.1016/j.jep.2013.08.015. Epub 2013 Aug 22
  7. 錢秋鳳 (1995)。<西洋參不良反應文獻概述>。南京中醫藥大學學報,6。
  8. Lee N-, Son C- (2011) Systematic Review of Randomized Controlled Trials Evaluating the Efficacy and Safety of Ginseng. JAMS Journal of Acupuncture and Meridian Studies, 4, 2, 85-97.
  9. Kitts DD, Hu C (2000) Efficacy and safety of ginseng. Public Health Nutr., 3, 4, 473-485.

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