科
药用部位
主治
脾胃虚弱,倦怠乏力,心悸气短,咳嗽痰多,脘腹、四肢挛急疼痛,痈肿疮毒,缓解药物毒性、烈性
注意事项
不宜与大戟、芫花、甘遂同用
不良反应
长时间(6周)超量服用(50g/day)可导致假性醛固酮增多症,其中包括钾缺乏,钠潴留,水肿,高血压和体重增加 [1,2,3]
可导致肌红蛋白尿和肌肉病变 [4]
在慢性乙肝患者身上可见肝毒性 [5]
与西药同用对心血管系统的不良反应 [6]
参考资料
Bradley PR, ed. British herbal compendium, Vol. 1. Bournemouth, British Herbal Medicine Association, 1992:145–148.
Epistein MT et al. Effects of eating liquorice on the renin-angiotensin aldosterone axis in normal subjects. British medical journal, 1977, 1:488–490.
Stewart PM et al. Mineralocorticoid activity of liquorice: 11- hydroxysteroid dehydrogenase deficiency comes of age. Lancet, 1987, ii:821–824.
Caradonna P et al. Acute myopathy associated with chronic licorice ingestion: Reversible loss of myoadenylate deaminase activity. Ultrastructural pathology, 1992, 16:529–535.
何吉芬 (2010)。<浅谈甘草及其制剂的毒副作用>。中国中医药现代远程教育,23。
Yuen MF, Tam S, Fung J, Wong D, Wong B, Lai CL (2006) Traditional Chinese medicine causing hepatotoxicity in patients with chronic hepatitis B infection: a 1-year prospective study. Aliment.Pharmacol.Ther., 24, 8, 1179-1186.