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吳茱萸
ENG
Medicinal Evodia Fruit
LATIN
Evodiae Fructus
Medicinal Group Interior-warming medicinal
Source

Dried nearly ripe fruit of Evodia rytaecarpa (Juss.) Benth., Evodia rutaecarpa (Juss.) Benth. var. officinalis (Dode) Huang or Evodia rutaecarpa (Juss.) Brnth. var. bodinieri (Dode) Huang (Fam. Rytaceae)

Nature and Flavors pungent, bitter; hot; slightly toxic
Meridian Affinity Liver, Spleen, Kidney, Stomach
Actions

To dispel cold and allviate pain, direct qi downward to relieve vomiting, and check diarrhea by assist yang

Family

Rytaceae

Part used

Fruit

Indications

Headache related to limbs reverting yin; abdominal colic; weakness and edema of the legs; dysmenorrhea; epigastric distension and pain with vomiting and acid regurgitation; diarrhea occurring before dawn daily; hypertension. External use for ulcers in the mouth

Research Findings

  • Growing Research Findings demonstrates that evodiamine possesses anti-cancer activities both in vitro and in vivo by inhibiting proliferation, invasion and metastasis, inducing apoptosis of a variety of tumor cell lines.[1]
  • Evodiamine and its derivatives are experimentally explored for their anti-cancer, anti-diabetic and anti-inflammatory properties.[2]

Cautions

No Data.

Report on adverse effect

Cause liver toxicity in orally fed mice [3]

Reference

Reference

  1. Jiang J, Hu C. (2009). Evodiamine: a novel anti-cancer alkaloid from Evodia rutaecarpa. Molecules. , 14(5):1852-9. doi: 10.3390/molecules14051852.
  2. Gavaraskar K, Dhulap S, Hirwani RR. (2015). Therapeutic and cosmetic applications of Evodiamine and its derivatives--A patent review. Fitoterapia. , 106:22-35. doi: 10.1016/j.fitote.2015.07.019. Epub 2015 Aug 6.
  3. 孫蓉、黃偉 (2012)。<吳茱萸水提組分鎮痛及伴隨毒副作用研究>。中國藥物警戒,11。

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